Timothy S. Catlett

Email: tcatlett@wisc.edu

Timothy Catlett

I utilize a pluripotent stem cell model to investigate guidance mechanisms in derived human neurons of the early CNS. I hope to elucidate neurite outgrowth and guidance responses to cues and their underlying intracellular signaling cascades, with an emphasis on the role of local protein synthesis at the growth cone. Stem cell modeling also facilitates our study of guidance phenotypes occurring in human neurodevelopmental diseases including Autism Spectrum Disorders.